The new edition of this highly successful annual pocket guide presents clinicians with the most recent information in the field of antimicrobial therapy and infectious diseases.
Written by recognised experts in infectious disease, this edition discusses serum and urinary spectrum summaries of antibiotics and clinically relevant pharmacokinetics. Completely new sections on Antibiotic Stewardship, IV-to-PO Switch Therapy, and differentiation of colonisation and infection, are also included.
Unique features of this book include clinical synopses of common and uncommon infections worldwide, differential diagnosis of infectious diseases and non-infectious mimics, antibiotic IV-to-PO switch therapy options for infectious diseases; and HIV, HCV, Peds ID, antibiotic prophylaxis and immunisations, chest film differential diagnosis atlas, and gram stain atlas.
◾Fifteenth edition presenting most recent information in field of antimicrobial therapy and infectious disease
◾Includesmany new topics
◾Authored by leading experts in the field
Cheston B Cunha MD
Director, Antibiotic Stewardship Program and Infectious Disease, Division of Infectious Disease, Rhode Island Hospital & Miriam Hospital, Rhode Island; Assistant Professor of Medicine, Brown University Alpert Medical School, USA
Burke A Cunha MD MACP
Chief, Infectious Disease Division, Winthrop-University Hospital, Mineola, New York; Professor of Medicine, State University of New York School of Medicine
Stony Brook, New York, USA
Overview of Antimicrobial Therapy Factors in Antibiotic Selection Spectrum Tissue Penetration Antibiotic Resistance Potential Safety Profile Cost Factors in antibiotic Dosing Dosing in Renal / Hepatic Insufficiency Microbiology and Susceptibility Testing In Vitro vs. In Vivo Susceptibility PK/PD and Other Considerations in Antimicrobial Therapy Bactericidal vs.Bacteriostatic Antibiotics Monotherapy vs. Combination Therapy Oral Antibiotic Therapy for Serious Systemic Infections IV-to- PO Switch Therapy Bioavailability of Oral Antibiotics OPAT Duration of Therapy Empiric vs. Specific Antibiotic Therapy Colonisation vs. Infection Positive Blood Cultures vs. Bacteremia (MSSA, MRSA, CoNS) Diabetic Foot Ulcers Sacral Ulcers Drug Fever Relative Bradycardia Antibiotic Failure Antibiotic Stewardship Principles and Practice Empiric Therapy Based On Clinical Syndrome CNS Infections Acute Bacterial Meningitis Acute Nonbacterial/Chronic Meningitis Encephalitis Brain Abscess/Subdural Empyema/ Cavernous Vein Thrombosis/Intracranial Suppurative Thrombophlebitis HEENT Infections Facial/Periorbital Cellulitis Bacterial Sinusitis Keratitis Conjunctivitis Chorioretinitis Endophthalmitis External Otitis Acute Otitis Media Mastoiditis Suppurative Parotitis Pharyngitis Thrush (Oropharyngeal Candidiasis) Mouth Ulcers/Vesicles Deep Neck Infections, Lemierre’s Syndrome, Severe Dental Infections Epiglottitis Lower Respiratory Tract Infections Acute Bacterial Exacerbation of Chronic Bronchitis Mediastinitis Community-Acquired Pneumonia Zoonotic Atypical Pneumonia Lung Abscess/Empyema Nursing Home-Acquired Pneumonia NosocomialPneumonia Cardiovascular Infections Subacute Bacterial Endocarditis Acute Bacterial Endocarditis Prosthetic Valve Endocarditis Pericarditis/Myocarditis Central IV Line/Pacemaker Infections Vascular Graft Infections Gastrointestinal Tract Infections Esophagitis Peptic Ulcer Disease Gastric Perforation Diarrhea/Typhoid (Enteric) Fever Cholecystitis CholangitisGallbladder Wall Abscess/Perforation Acute Pancreatitis Pancreatic Abscess/Infected Pancreatic Pseudocyst Liver Abscess Hepatosplenic Candidiasis Granulomatous Hepatitis Viral Hepatitis Intraabdominal or Pelvic Peritonitis/Abscess (Colitis, Appendicitis, Diverticulitis, Septic Pelvic Thrombophlebitis, Spontaneous Bacterial Peritonitis, CAPD-Associated Peritonitis, TB Peritonitis) Genitourinary Tract Infections Dysuria-Pyuria Syndrome Cystitis Catheter-Associated Bacteriuria/Candiduria Epididymitis Acute Pyelonephritis ChronicPyelonephritis Renal TB Renal Abscess (Intrarenal/Perinephric) Prostatitis/Prostatic Abscess Urosepsis Pelvic Inflammatory Disease, Salpingitis, Tuboovarian Abscess, Endometritis/Endomyometritis, Septic Abortion Sexually Transmitted Diseases Urethritis/Cervicitis Vaginitis/Balanitis Genital Vesicle Genital Ulcers Suppurating Inguinal Adenopathy Genital/PerianalWarts Syphilis Bone and Joint Infections Septic Arthritis/Bursitis Lyme Disease/Lyme Arthritis Infected Joint Prosthesis Osteomyelitis Skin and Soft Tissue Infections Cellulitis, Erysipelas, Mastitis Complicated Skin/Skin Structure Infections (cSSSIs) Skin Ulcers Skin Abscesses/Infected Cysts (Skin Pustules/Boils, Furunculosis) Skin Vesicles (Non-Genital) Wound Infection Superficial Fungal Infections Skin/Nail Skin Infestations Ischiorectal/Perirectal Abscess Sepsis/Septic Shock Febrile Neutropenia Transplant Infections Bacteremia Candidemia CMV/HHV-6/BK Virus EVB/PTLD RSV Adenovirus Encephalitis/Meningitis Brain Abscess/Mass Lesions Focal/Segmental Pulmonary Infiltrates Diffuse Pulmonary Infiltrates Viral Hepatitis Toxin-Mediated Infectious Diseases Toxic Shock Syndrome Botulism Tetanus Diphtheria Bioterrorist Agents Anthrax Tularemia Pneumonia Pneumonic Plague Botulism Smallpox Ebola Antibiotic Susceptibility Profiles And Initial Therapy Of Isolates Pending Susceptibility Results Antibiotic Susceptibility Profiles (Penicillins, Macrolides, Tetracyclines, and Others) Antibiotic Susceptibility Profiles (Cephalosporins) Antibiotic Susceptibility Profiles (Aminoglycosides, Fluoroquinolones, Carbapenems, and Others) Gram Stain Characteristics of Isolates (by Morphology Arrangement, Oxygen Requirements) Alphabetical Index of Isolates Key Factors in Antibiotic Selection (Isolate Known) Antibiotic Resistance Potential Aerobic IsolatesCapnophilic Isolates Anaerobic Isolates Yeast/Fungi Empiric Antibiotic Therapy of Selected Problem Pathogens Gram Stain/Giemsa Stain Technique CSF Gram Stain Sputum Gram Stain Urine Gram Stain Fecal Gram Stain Parasites, Fungi, Unusual Organisms Blood Pathogens Microfilaria in Blood Trypanosomes in Blood Spirochetes in Blood Intracellular Inclusion Bodies in Blood CSF/Brain Pathogens Cysts/Mass Lesions in CSF/Brain Lung Pathogens Pulmonary Cystic Lesions/Masses Pulmonary Coin Lesions Pulmonary Infiltrates/Mass Lesions Heart Pathogens Chagas’ Disease Liver Pathogens Liver Flukes Cystic Masses in Liver Hepatomegaly Stool/Intestines Pathogens Intestinal Protozoa Intestinal Nematodes (Roundworms) Intestinal Cestodes (Tapeworms) Intestinal Trematodes (Flukes/Flatworms) Other Intestinal Infections Skin/Muscle Pathogens Infiltrative Skin/Subcutaneous Lesions Infiltrative Skin Lesions ± Ulcers/Sinus Tracts/Abscesses Skin Vesicles/Bullae Subcutaneous Serpiginous Lesions Skin Papules/Nodules/Abscesses Rickettsia (Fever/Petechial Skin Rash) Other Skin Lesions Myositis HIV Infection Overview Stages of HIV Infection Acute (Primary) HIV Infection Approach to HIV Testing Initial Assessment of HIV Patients Indications for Treatment of HIV Infection Antiretroviral Treatment Antiretroviral Treatment Failure Opportunistic Infections in HIV Disease Treatment of Opportunistic Infections Treatment of Other Opportunistic Infections in HIV HIV Coinfections (HBV/HCV) Prophylaxis And Immunizations Surgical Prophylaxis Post-Exposure Prophylaxis Chronic Medical Prophylaxis/Suppression HIV Pre-Exposure Prophylaxis (PrEP) HIV Post-Exposure Prophylaxis (PEP) HIV Opportunistic Infections Transplant Prophylaxis Endocarditis Prophylaxis Travel Prophylaxis Malaria Prophylaxis Tetanus Prophylaxis Immunizations Pediatric Infectious Diseases And Pediatric Drug Summaries CNS Infections HEENT Infections Lower Respiratory Tract Infections Vascular Infections Gastrointestinal Infections Bone and Joint Infections Skin and Soft Tissue Infections Common Pediatric Antimicrobial Drugs Chest X-Ray Atlas Unilateral Focal Segmental/ Lobar Infiltrate without Effusion Unilateral Focal Segmental/Lobar Infiltrate With Effusion Unilateral Ill-Defined Infiltrates Without Effusion Unilateral Ill-Defined Infiltrates With Effusion Bilateral Infiltrates Without Effusion Bilateral Infiltrates With Effusion Cavitary Infiltrates (Thick-Walled) Cavitary Infiltrates (Thin-Walled) Infectious Disease Differential Diagnosis Antibiotic Pearls & Pitfalls Antimicrobial Drug Summaries Appendix Index Color Atlas of CSF, Sputum, and Urine Gram Stains & Fungal Stains.