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Geriatric Oncology 3Ed
Geriatric Oncology 3Ed
Edición/Edição:
Autores: Gumersindo Pérez-Manga; Lazzaro Repetto
Editorial:
ISBN: 9788478855209
Formato: Tapa Dura/Hardback
Nº volumenes: 1 Páginas: 295
Año publicación/Ano de publicação: 2010
Disponibilidad/Disponibilidade: Inmediata
Precio/Preço : 120,75 € 114,71 € (119,30€ iva incluído)
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Geriatric Oncology 3Ed Cardiooncología Clínica + ExpertConsult
· Geriatric Oncology 3Ed (Gumersindo Pérez-Manga; Lazzaro Repetto)
· Cardiooncología Clínica + ExpertConsult (Joerg Herrmann)
221,71 € 210,62 €
Descripción/Descrição
Introduction ....................................................................... XI
1. Epidemiology of geriatric oncology ......................... 1
M.L.G. Janssen-Heijnen, S.A.M. van de Schans
2. Comprehensive Geriatric Assessment ..................... 19
M.A. Viloria Jiménez, P. Gil Gregorio
3. Surgery in Older Cancer Patients ............................. 33
S. R. Kristjansson, S. Gaskell,
R. A. Audisio
4. Radiotherapy in the Elderly ...................................... 41
M. de las Heras, P Alcántara, S. Córdoba, J.A. Corona,
J.L. Tisaire, G. Vázquez, F. Puebla
5. Chemotherapy in the elderly patient ....................... 59
H. Nortier, H. Wildiers
6. Hormone therapy ....................................................... 65
G. Pérez-Manga, P. Khosravi Shahi,
Y. Izazurgaza Perón, Mª E. Pérez Cañón
7. The appropiate use of Molecular Therapy .............. 73
E. Pineda, L. Visa, P. Gascón
8. Breast Cancer In Elderly Patients ............................. 81
A. Lluch Hernández, J. A. Pérez-Fidalgo,
I. Chirivella González
9. Treatment of colorectal cancer in the elderly .......... 93
A. Custodio Carretero, J. Bobokova, A. Irles Quiles,
J. Sastre Valera, J. Puente Vázquez, E. Díaz-Rubio García
10. Non-colorectal digestive cancer in the geriatric
patient ........................................................................... 113
P. García Alfonso, C. Grávalos, A. Muñoz Martín,
J.M. Tellado
11. Lung Cancer ................................................................ 129
C. Gridelli, A. Rossi, P. Maione
12. Gynecological tumors in geriatric oncology ........... 149
E. Foti, G. Scambia
13. Management of advanced bladder and renal
cancer in the elderly ................................................... 157
J. Bellmunt Molins, M. Guix Arnau
14. Prostate cancer ............................................................. 171
F. Boccardo, M. Messina, F. Ricci,
S. Sanguineti, G. Schiavone, L. Tomasello
15. Lymphoma ................................................................... 187
A. Gutiérrez García, J. Rodríguez Díaz-Pavón
16. Brain tumours in older persons ................................ 203
M. Benavides Orgaz, J. Martínez Galán,
G. Durán Ogalla, M. Ángel Arraez Sánchez,
V. Gutiérrez Calderón, I. Ales Díaz
17. Head and Neck Carcinoma in the Elderly .............. 221
J. J. Cruz Hernandez, R. López Castro,
E. Fonseca Sánchez
18. Cutaneous neoplasms ................................................ 235
C. Guillén, A. Martorell-Calatayud,
B. Echeverría García
19. The management of toxicities in elderly patients ... 251
C. Bernard-Marty, R. Castany-Prado
20. Oncological rehabilitation of the elderly ................. 259
D. Dini, G. Forno, A. Gozza
21. The 3D’s in elderly patients with cancer:
depression, delirium, dementia ................................ 275
G. Gambassi
22. Taking care of the older cancer patiens:
clinical setting .............................................................. 287
S. Monfardini, U. Basso
Index ................................................................................... 293

The incidence of all cancers increases with age and cancer is a major cause of morbidity and mortality in the older
population in Europe as well as in the United States. The increasing prevalence of cancer in the aging population
represents a new challenge for clinicians and researchers and has dramatic implications for the organization and costs
of health care services. Today about 50% of the diagnosis of new cancer occurs in patients over 70 yrs. Nevertheless,
there is a lack of clinical guidelines to support the choice of the best treatment options for this age group and few
patients are referred to existing trials. The difficulties in the definitions of the aging process and the biological age,
in the recognition of age-related relevant characteristics, which affect treatment program and disease outcome, may
explain the limited attention so far deserved to geriatric-oncology by practicing oncologists.
Recently, the dramatic increase of the age of the most likely cancer patient in our clinics and the awareness of the
conditions that may complicate usual cancer treatment in elderly patients have generated more and more attention to
the need to stimulate the oncologic research in older patient.
The differences in the biological behavior of cancer, a shorter life expectancy, higher vulnerability to stress conditions
in the elderly with respect to younger adults highlight the need to define new prognostic factors and to plan different
therapeutic strategies. In the past decade a better understanding of the biological interactions of aging and cancer, of
the differences of cancer growth with age, of the different behaviors and expectations towards the diagnosis and the
management of cancer of the elderly population, drove the development of a new methodology of clinical research in
geriatric-oncology and a new clinical approach to elderly patients.
Although over half of the patients diagnosed with cancer are 70 years and older, we lack authoritative evidencebased,
clinical practice guidelines that include recommendations to support the selection of the best options for the
evaluation and for the management of elderly cancer patients.
In the last years reliable progresses have been made in oncology with the introduction in the clinical practice of
new agents, including new target therapies, and better supportive therapies. This allows extending the boundaries
of cancer treatment and prognosis. Unfortunately we have limited knowledge of the safety and efficacy of these new
achievements in the elderly patients but this should not prevent their use in this population. In order to properly
approach these patients several questions need answers: how to evaluate the functional, psychological and physical
status in the older person; which parameters are important and useful to be evaluated; are standard and reproducible
assessment instruments available; are their predictive and prognostic roles defined; and finally, do we have evidence
of their importance in leading the therapeutic decisions.
This book explores and summarizes relevant results from trials performed on older patients in order to provide
the readers with a condensed review of the field and to promote better assessment and management of older patient
based on available knowledge. We also hope to raise interest among a new generation of oncologists and geriatricians
offering a frame of reference for a stimulating dialogue in the interest of their geriatric-oncology patients.
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