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Description

This book provides up to date information on disorders that affect the kidneys as well as the joints. These disorders often affect several systems in the body and many have an immunological basis. The majority of chapters in this book focus on specific diseases and examine their aetiology, pathogenesis, immunological basis and pathology. In addition the clinical features, current approaches to treatment and outcome are described. Overall these chapters provide a balanced view of current understanding of these conditions. The major syndromes of Rheumatologic diseases reviewed include Systemic Lupus Erythematosus, the Vasculitides (including Wegener's granulomatosis, Polyarteritis Nodosa, Microscopic polyangiitis, Churg Strauss Syndrome, Takayasu's disease and Henoch-Schonlein Purpura, and Systemic Sclerosis. Other Chapters cover amyloidosis and Hepatitis B and C associated systemic disease. Finally there are chapters on the nephrotoxicity of drugs used in the treatment of rheumatologic diseases and also on rheumatologic complications following renal transplantation. The information in the book is up to date and brings together in a concise manner information that is otherwise widely scattered in the literature. This book should appeal to nephrologists and rheumatologists as well as all those interested in the care of patients with systemic autoimmune disorders.


Readership: General reference for specialist nephrologists and rheumatologists as well as those in training.

Contents/contributors
Part I: Lupus nephritis
Bickerstaff and Isenberg: An overview of SLE
Cameron: Clinical manifestations of lupus nephritis
Schwartz: Lupus nephritis: histology
Walport and Robson: Lupus nephritis: complement in lupus
Madaio: Pathogenesis of lupus nephritis for rheumatology and the kidney
Takada, Boumpas and Illei: Lupus nephritis: treatment - pulse cyclophosphamide
Moroni and Ponticelli: Lupus nephritis: treatment with continuous therapies
Sammaritano and Lockshin: SLE in pregnancy
Levine and Rauch: Renal involvement in the anti-phospholipid syndrome
Part II: Vasculitis
Jennette, Falk and Thomas: Vasculitis classification
Ben-Smith and Savage: Immunopathogenesis of systemic vasculitis
Ferrario and Rastaldi: Pathology of vasculitis
Jennette, Falk and Thomas: Clinical presentation and treatment of renal vasculitis
Guillevin: Polyarteritis nodosa: clinical characteristics, outcome, and treatment
Coppo and Amore: Vasculitis (ANCA negative): Henoch-Schönlein purpura
Jha and Chugh: Takayasu's arteritis
Part III: Systemic sclerosis
Simms and Korn: Systemic sclerosis: the spectrum, immunopathogenesis, clinical features, and treatment
Part IV: Rheumatoid arthritis
Adu and Tse: Rheumatoid arthritis, mixed connective tissue disease and polymyositis
Part V: Amyloidosis
Lachmann and Hawkins: Amyloidosis: pathogenesis and diagnosis
Lachman and Hawkins: Amyloidosis: rheumatic disease and amyloid: clinical features and treatment
Kyle: Primary amyloidosis
Ronco: Light-chain and heavy-chain deposition diseases
Part VI: Hepatitis associated systemic disease
Pusey and Salama: Rheumatologic diseases associated with interstitial nephritis
Lai: Hepatitis B associated renal diseases
Part VII: Drug nephrotoxicity
Wahba and Bennett: The nephrotoxicity of calcineurin inhibitors
Tse and Adu: Non-steroidal anti-inflammatory drugs and the kidney
Broe: Nephrotoxicity of drugs used in rheumatology: analgesic nephropathy
Bingham and Emery: Renal toxicity of anti-rheumatic drugs
Part VIII: Interstitial nephritis and gout
Salama and Pusey: Rheumatologic diseases associated with interstitial nephritis
Brown and Griffith: Dialysis arthropathy
Part IX: Rheumatological complications of dialysis and transplantation
Griffith and Brown: Dialysis arthropathy
Karim, Lawson and Emery: Rheumatological complications of renal disease and transplantation
Index