This book provides up to date information on disorders that affect the kidneys as well as the joints. These disorders often affect several systems in the body and many have an immunological basis. The majority of chapters in this book focus on specific diseases and examine their aetiology, pathogenesis, immunological basis and pathology. In addition the clinical features, current approaches to treatment and outcome are described. Overall these chapters provide a balanced view of current understanding of these conditions. The major syndromes of Rheumatologic diseases reviewed include Systemic Lupus Erythematosus, the Vasculitides (including Wegener's granulomatosis, Polyarteritis Nodosa, Microscopic polyangiitis, Churg Strauss Syndrome, Takayasu's disease and Henoch-Schonlein Purpura, and Systemic Sclerosis. Other Chapters cover amyloidosis and Hepatitis B and C associated systemic disease. Finally there are chapters on the nephrotoxicity of drugs used in the treatment of rheumatologic diseases and also on rheumatologic complications following renal transplantation. The information in the book is up to date and brings together in a concise manner information that is otherwise widely scattered in the literature. This book should appeal to nephrologists and rheumatologists as well as all those interested in the care of patients with systemic autoimmune disorders.
Readership: General reference for specialist nephrologists and rheumatologists as well as those in training.
Contents/contributors Part I: Lupus nephritis Bickerstaff and Isenberg: An overview of SLE Cameron: Clinical manifestations of lupus nephritis Schwartz: Lupus nephritis: histology Walport and Robson: Lupus nephritis: complement in lupus Madaio: Pathogenesis of lupus nephritis for rheumatology and the kidney Takada, Boumpas and Illei: Lupus nephritis: treatment - pulse cyclophosphamide Moroni and Ponticelli: Lupus nephritis: treatment with continuous therapies Sammaritano and Lockshin: SLE in pregnancy Levine and Rauch: Renal involvement in the anti-phospholipid syndrome Part II: Vasculitis Jennette, Falk and Thomas: Vasculitis classification Ben-Smith and Savage: Immunopathogenesis of systemic vasculitis Ferrario and Rastaldi: Pathology of vasculitis Jennette, Falk and Thomas: Clinical presentation and treatment of renal vasculitis Guillevin: Polyarteritis nodosa: clinical characteristics, outcome, and treatment Coppo and Amore: Vasculitis (ANCA negative): Henoch-Schönlein purpura Jha and Chugh: Takayasu's arteritis Part III: Systemic sclerosis Simms and Korn: Systemic sclerosis: the spectrum, immunopathogenesis, clinical features, and treatment Part IV: Rheumatoid arthritis Adu and Tse: Rheumatoid arthritis, mixed connective tissue disease and polymyositis Part V: Amyloidosis Lachmann and Hawkins: Amyloidosis: pathogenesis and diagnosis Lachman and Hawkins: Amyloidosis: rheumatic disease and amyloid: clinical features and treatment Kyle: Primary amyloidosis Ronco: Light-chain and heavy-chain deposition diseases Part VI: Hepatitis associated systemic disease Pusey and Salama: Rheumatologic diseases associated with interstitial nephritis Lai: Hepatitis B associated renal diseases Part VII: Drug nephrotoxicity Wahba and Bennett: The nephrotoxicity of calcineurin inhibitors Tse and Adu: Non-steroidal anti-inflammatory drugs and the kidney Broe: Nephrotoxicity of drugs used in rheumatology: analgesic nephropathy Bingham and Emery: Renal toxicity of anti-rheumatic drugs Part VIII: Interstitial nephritis and gout Salama and Pusey: Rheumatologic diseases associated with interstitial nephritis Brown and Griffith: Dialysis arthropathy Part IX: Rheumatological complications of dialysis and transplantation Griffith and Brown: Dialysis arthropathy Karim, Lawson and Emery: Rheumatological complications of renal disease and transplantation Index