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The Lymphoid Neoplasms 3ed
The Lymphoid Neoplasms 3ed
Edición/Edição: 3rd
Autores: Ama Rohatiner; V. Diehl; Claire Dearden; Randy Gascoyne; Harald Stein; M Potter; P. Boffetta; Ian Magrath
Editorial:
ISBN: 9780340809471
Formato: Rústica/Paperback
Nº volumenes: 1 Páginas: 1344
Año publicación/Ano de publicação: 2009
Disponibilidad/Disponibilidade: 15 días
Precio/Preço : 249,42 € 236,94 € (246,42€ iva incluído)
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Descripción/Descrição
This comprehensive and authoritative reference covers all aspects of the group of disorders collectively known as the lymphoid neoplasms. The reader is taken through a description of its normal cellular origins and the molecular genetic abnormalities that can lead to this group of conditions, a section of the book that has been considerably strengthened for this third edition, to the environmental factors that may be relevant to disease development, and, finally, to the pragmatic aspects of disease management. The authors synthesise for the reader apsects of current knowledge and likely future developments, and direct them to the appropriate resources should they wish to pursue particular avenues of scientific or literature research.




Now includes Hodgkin's Disease and the acute lymphoblastic leukemias – a ‘one-stop-shop
Improved consistency of style, structure and approach between chapters
New text features – summary points, text boxes, reference annotation
Improved coverage of the basic science aspects


Contents:

Table of Contents:
Part I: INTRODUCTION
1. Conceptual basis
2. History
Part II: EPIDEMIOLOGY
3. Descriptive epidemiology
4. Causes and prevention of lymphomas
5. Immunological and genetic predisposition
6. Retroviruses
7. Herpesviruses
8. Other microorganisms
Part III: IMMUNOBIOLOGY
9. Overview of the immune system
10. Ontogeny of T and NK cells
11. Ontogeny of B cells
12. Cellular immunobiology of lymph nodes and spleen
13. Cellular immunobiology of extranodal lymphoid tissue
14. Terminal B cell differentiation
15. Interleukins and the cytological composition of lymphoid neoplasms
16. Lymphocyte homing: relevance to clinical syndromes
17. Pathobiology of apoptosis in lymphocytes
18. Somatic hypermutation mechanism in the pathogenesis of lymphoid neoplasms
19. Animal models of human lymphoid neoplasms
Part IV: CLASSIFICATION AND PATHOGENESIS
20. Pathological anatomy of the immune system
21. The classification of lymphoid neoplasia
22. Borderland between pathological entities: composite lymphomas
23. Cytogenetics of lymphoid neoplasia
24. Molecular basis of chromosomal translocations
25. Molecular genetics of lymphoid neoplasia
26. Gene expression patterns in lymphoma classification
27. Immunodeficieny, inherited and acquired, and lymphomagenesis
28. Chronic inflammation, including autoimmunity, and lymphogenesis
Part V: PATHOLOGY AND PATHOGENESIS OF SPECIFIC LYMPHOMAS
29. Lymphoblastic lymphomas and leukemias
30. Small cell leukemias and lymphomas
31. Hairy cell leukemia
32. Mantle cell lymphomas
33. Marginal zone lymphoma
34. Follicular lymphoma
35. Burkitt's lymphoma
36. Diffuse large B-cell lymphomas
37. Hodgkin's lymphoma
38. Plasma cell neoplasms
39. NK cell lymphomas and leukemias
40. Anaplastic large cell lymphomas
41. Mycosis fungoides and Sezary Syndrome
42. Other peripheral T cell lymphomas
Part VI: PRESENTING FEATURES, DIAGNOSIS, STAGING
43. Presenting features of lymphoid neoplasms
44. Histological diagnosis
45. Immunophenotyping as a diagnostic tool
46. Genetic studies in determining diagnosis and assessing prognosis
47. Radiological, ultrasound and nuclear magnetic resonance imaging
48. Radionuclide imaging
49. Staging systems and staging investigations
50. Special aspects of diagnosis in developing countries
51. Imaging in Developing Countries
Part VII: GENERAL PRINCIPLES OF MANAGEMENT
52. Emergency management
53. Systemic therapy
54. Radiation therapy
55. Surgery in diagnosis and treatment
56. Assessment of response and follow up
57. Supportive care in lymphoid neoplasia
58. Prognostic factors and risk adaptation
59. Second line therapy
60. High dose therapy with stem cell rescue
61. Management of lymphoid neoplasms during pregnancy
62. Management of lymphoid neoplasms in the infant
63. Management of lymphoid neoplasms in the elderly
64. Management of lymphomas at extranodal locations
65. Management of lymphomas in developing countries
66. Late effects of treatment/quality of life
Part VIII: MANAGEMENT OF SPECIFIC DISEASES
67. Lymphoblastic lymphoma and leukemia in children
68. Lymphoblastic lympomas and leukemias in adults
69. Small B cell lymphomas and leukemias with hairy cell lymphoma
70. Mantle cell lymphoma
71. Marginal zone, including MALT associated lymphomas
72. Follicular lymphoma
73. Burkitt and Burkitt like lymphomas/leukemia in children
74. Burkitt and Burkitt like lymphoma/leukemia in adults
75. Diffuse large B cell lymphoma in children
76. Diffuse large B cell lymphomas in adults
77. Hodgkin's lymphoma in adults
78. Hodgkin's lymphoma in children
79. Plasma cell neoplasms
80. Leukemias and lymphomas of NK cell origin
81. Anaplastic large cell lymphoma in adults
82. Anaplastic large cell lymphoma in children
83. Mycosis fungoides and Sezary Syndrome
84. Adult T-cell leukemia/lymphoma
85. Peripheral T cell lymphomas
86. HIV-associated lymphomas
87. Lymphoid neoplasms in individuals with underlying chronic diseases
88. Unusual lymphoid neoplasms in children
Part IX: FUTURE DIRECTIONS IN DIAGNOSIS AND TREATMENT
89. Applications of genomic and epigenetic studies
90. New drugs
91. Monoclonal antibody therapy
92. Cellular therapies
93. Vaccine therapies
94. Normal Cellular Infiltrates in Diagnosis, Prognosis and Management
95. Molecular therapy
96. Viral Targeted Therapies






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