For many years, addiction research focused almost exclusively on men. Yet scientific awareness of sex and gender differences in substance use disorders has grown tremendously in recent decades. This volume brings together leading authorities to review the state of the science and identify key directions for research and clinical practice. Concise, focused chapters illuminate how biological and psychosocial factors influence the etiology and epidemiology of substance use disorders in women; their clinical presentation, course, and psychiatric co morbidities; treatment access; and treatment effectiveness. Prevalent substances of abuse are examined, as are issues facing special populations.
Contents Ch. 1 Substance Abuse across the Lifespan in Women by Monica L. Zilberman 3 Ch. 2 Research Design and Methodology in Studies of Women and Addiction by Stephanie Collins Reed and Suzette M. Evans 14 Ch. 3 Neuroactive Gonadal Steroid Hormones and Drug Addiction in Women by Jennifer L. Newman and Nancy K. Mello 35 Ch. 4 Stress, Neuroendocrine Response, and Addiction in Women by Helen Fox and Rajita Sinha 65 Ch. 5 Sex Differences in the Transmission of Substance Use Disorders by Amanda Kalaydjian and Kathleen Ries Merikangas 84 Ch. 6 Sex Differences and Neurotransmitter Systems in Addiction by Teresa A. Pigott and Maryann H. Walker and Scott A. Teitelbaum and Ching-ju Lu 99 Ch. 7 Sex Differences in Pharmacokinetics and Pharmacodynamics by C. Lindsay DeVane 118 Ch. 8 Gender, Cognition, and Addiction by Simona Sava and Alexandra McCaffrey and Deborah A. Yurgelun-Todd 133 Ch. 9 The Roles of Sex Differences in the Drug Addiction Process by Amanda Elton and Clinton D. Kilts 147 Ch. 10 Comorbidity of Substance Use Disorders with Independent Mood and Anxiety Disorders in Women: Results from the National Epidemiologic Survey on Alcohol and Related Conditions by Rise B. Goldstein 173 Ch. 11 Depression and Substance Use Disorders in Women by Helen M. Pettinati and Jennifer G. Plebani 193 Ch. 12 Gender, Anxiety, and Substance Use Disorders by Kathleen T. Brady and Karen Hartwell 209 Ch. 13 Co-Occurring Eating and Substance Use Disorders by Lisa R. Cohen and Susan M. Gordon 225 Ch. 14 Trauma, Posttraumatic Stress Disorder, and Addiction among Women by Denise Hien 242 Ch. 15 Psychotic Disorders in Women with Substance Abuse by Kim-Chi Nguyen and E. Sherwood Brown 257 Ch. 16 Concurrent Personality Disorders and Substance Use Disorders in Women by Lisa A. Burckell and Shelley McMain 269 Ch. 17 Gender-Specific Treatment for Women with Substance Use Disorders by Shelly F. Greenfield and Sandrine Pirard 289