Geriatric Oncology 3Ed

114,71 €
Disponible
ISBN
9788478855209
Edición
Autores
Gumersindo Pérez-Manga, Lazzaro Repetto
Editorial
Aula Médica
Fecha Publicacion
20 nov. 2010
Características
N/D
Introduction ....................................................................... XI 1. Epidemiology of geriatric oncology ......................... 1 M.L.G. Janssen-Heijnen, S.A.M. van de Schans 2. Comprehensive Geriatric Assessment ..................... 19 M.A. Viloria Jiménez, P. Gil Gregorio 3. Surgery in Older Cancer Patients ............................. 33 S. R. Kristjansson, S. Gaskell, R. A. Audisio 4. Radiotherapy in the Elderly ...................................... 41 M. de las Heras, P Alcántara, S. Córdoba, J.A. Corona, J.L. Tisaire, G. Vázquez, F. Puebla 5. Chemotherapy in the elderly patient ....................... 59 H. Nortier, H. Wildiers 6. Hormone therapy ....................................................... 65 G. Pérez-Manga, P. Khosravi Shahi, Y. Izazurgaza Perón, Mª E. Pérez Cañón 7. The appropiate use of Molecular Therapy .............. 73 E. Pineda, L. Visa, P. Gascón 8. Breast Cancer In Elderly Patients ............................. 81 A. Lluch Hernández, J. A. Pérez-Fidalgo, I. Chirivella González 9. Treatment of colorectal cancer in the elderly .......... 93 A. Custodio Carretero, J. Bobokova, A. Irles Quiles, J. Sastre Valera, J. Puente Vázquez, E. Díaz-Rubio García 10. Non-colorectal digestive cancer in the geriatric patient ........................................................................... 113 P. García Alfonso, C. Grávalos, A. Muñoz Martín, J.M. Tellado 11. Lung Cancer ................................................................ 129 C. Gridelli, A. Rossi, P. Maione 12. Gynecological tumors in geriatric oncology ........... 149 E. Foti, G. Scambia 13. Management of advanced bladder and renal cancer in the elderly ................................................... 157 J. Bellmunt Molins, M. Guix Arnau 14. Prostate cancer ............................................................. 171 F. Boccardo, M. Messina, F. Ricci, S. Sanguineti, G. Schiavone, L. Tomasello 15. Lymphoma ................................................................... 187 A. Gutiérrez García, J. Rodríguez Díaz-Pavón 16. Brain tumours in older persons ................................ 203 M. Benavides Orgaz, J. Martínez Galán, G. Durán Ogalla, M. Ángel Arraez Sánchez, V. Gutiérrez Calderón, I. Ales Díaz 17. Head and Neck Carcinoma in the Elderly .............. 221 J. J. Cruz Hernandez, R. López Castro, E. Fonseca Sánchez 18. Cutaneous neoplasms ................................................ 235 C. Guillén, A. Martorell-Calatayud, B. Echeverría García 19. The management of toxicities in elderly patients ... 251 C. Bernard-Marty, R. Castany-Prado 20. Oncological rehabilitation of the elderly ................. 259 D. Dini, G. Forno, A. Gozza 21. The 3D’s in elderly patients with cancer: depression, delirium, dementia ................................ 275 G. Gambassi 22. Taking care of the older cancer patiens: clinical setting .............................................................. 287 S. Monfardini, U. Basso Index ................................................................................... 293 The incidence of all cancers increases with age and cancer is a major cause of morbidity and mortality in the older population in Europe as well as in the United States. The increasing prevalence of cancer in the aging population represents a new challenge for clinicians and researchers and has dramatic implications for the organization and costs of health care services. Today about 50% of the diagnosis of new cancer occurs in patients over 70 yrs. Nevertheless, there is a lack of clinical guidelines to support the choice of the best treatment options for this age group and few patients are referred to existing trials. The difficulties in the definitions of the aging process and the biological age, in the recognition of age-related relevant characteristics, which affect treatment program and disease outcome, may explain the limited attention so far deserved to geriatric-oncology by practicing oncologists. Recently, the dramatic increase of the age of the most likely cancer patient in our clinics and the awareness of the conditions that may complicate usual cancer treatment in elderly patients have generated more and more attention to the need to stimulate the oncologic research in older patient. The differences in the biological behavior of cancer, a shorter life expectancy, higher vulnerability to stress conditions in the elderly with respect to younger adults highlight the need to define new prognostic factors and to plan different therapeutic strategies. In the past decade a better understanding of the biological interactions of aging and cancer, of the differences of cancer growth with age, of the different behaviors and expectations towards the diagnosis and the management of cancer of the elderly population, drove the development of a new methodology of clinical research in geriatric-oncology and a new clinical approach to elderly patients. Although over half of the patients diagnosed with cancer are 70 years and older, we lack authoritative evidencebased, clinical practice guidelines that include recommendations to support the selection of the best options for the evaluation and for the management of elderly cancer patients. In the last years reliable progresses have been made in oncology with the introduction in the clinical practice of new agents, including new target therapies, and better supportive therapies. This allows extending the boundaries of cancer treatment and prognosis. Unfortunately we have limited knowledge of the safety and efficacy of these new achievements in the elderly patients but this should not prevent their use in this population. In order to properly approach these patients several questions need answers: how to evaluate the functional, psychological and physical status in the older person; which parameters are important and useful to be evaluated; are standard and reproducible assessment instruments available; are their predictive and prognostic roles defined; and finally, do we have evidence of their importance in leading the therapeutic decisions. This book explores and summarizes relevant results from trials performed on older patients in order to provide the readers with a condensed review of the field and to promote better assessment and management of older patient based on available knowledge. We also hope to raise interest among a new generation of oncologists and geriatricians offering a frame of reference for a stimulating dialogue in the interest of their geriatric-oncology patients.
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