Summarizes the field and indicates key directions
Explores and analyzes genomic variations
With numerous tables presenting the data systematically
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
Content Level » Research
Keywords » Cancer - Cardiovascular diseases - Immune response - NOD-like receptors - Pathogen-associated patterns - Toll-like receptors
Related subjects » Cancer Research - Cardiology & Angiology - Human Genetics - Immunology - Oncology & Hematology
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