Genomics of Pattern Recognition Receptors

146,99 €
Disponible
ISBN
9783034806879
Edición
Autores
A. Kutikhin, A. Yuzhalin
Editorial
Springer
Fecha Publicacion
23 feb. 2013
Características
N/D
Summarizes the field and indicates key directions Explores and analyzes genomic variations With numerous tables presenting the data systematically This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed. Content Level » Research Keywords » Cancer - Cardiovascular diseases - Immune response - NOD-like receptors - Pathogen-associated patterns - Toll-like receptors Related subjects » Cancer Research - Cardiology & Angiology - Human Genetics - Immunology - Oncology & Hematology
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