Plant Metabolic Networks
Edited by JÃ¶rg Schwender
Plants are the basis for human nutrition and are of increasing interest for the chemical industry as a source of chemical feed stocks. Fuels derived from plant biomass will increasingly replace fossil fuels in the future. In order to increase crop productivity, design new plant products, and create new energy crops, there is need for methods of qualitative and quantitative analysis of metabolism which are able to guide the rational re-design of metabolic networks.
In Plant Metabolic Networks recent advances in qualitative and quantitative analysis of metabolism are summarized to give an overview of the current state of knowledge. The book can be divided into three parts: First an introductory chapter (chapter 2), relating to the unique complexity of plant metabolism. The following three chapters describe how to analyze the components that make up the metabolic network, metabolites and enzymes. Finally, chapters 6 to 11 are devoted to network analysis and modeling. Contributions from different expert authors have been assembled to give a current view on plant metabolic networks, from the analysis of the molecular parts to approaches of mathematical modeling of plant metabolic networks at the cellular level.
JÃ¶rg Schwender received his Ph.D. in Biology in 1999 from the University of Karlsruhe / Germany. He is currently associate scientist in the biology department of Brookhaven National Laboratory, New York, USA. His main research interests are metabolic flux analysis and related approaches of modeling and analysis of metabolic networks in plants.
Students, graduate students, university teachers, industry researchers in the fields of plant science and plant pathology
Introduction.- Network definition.- Metabolite measurements.- Enzyme kinetics: theory and practice.- Quantification of Isotope label.- Data integration.- Topology of plant metabolic networks.- Network stoichiometry.- Steady state fluxes.- Dynamic flux analysis.- Kinetic modeling.- Subject Index.