Metabolism At A Glance 4th Ed.

39,90 € 38,37 €
Disponible
ISBN
9780470674710
Edición
Autores
Jack G. Salway
Editorial
Wiley
Fecha Publicacion
20 feb. 2017
Características
N/D
Metabolism at a Glance presents a concise, illustrated summary of metabolism in health and disease. This essential text is progressively appropriate for introductory through to advanced medical and biochemistry courses. It also provides a succinct review of inborn errors of metabolism, and reference for postgraduate medical practitioners and biomedical scientists who need a resource to quickly refresh their knowledge. Fully updated and extensively illustrated, this new edition of Metabolism at a Glance is now in full colour throughout, and includes new coverage of sports biochemistry; the metabolism of lipids, carbohydrates and cholesterol; glyceroneogenesis, á-oxidation and ù-oxidation of fatty acids. It also features the overlooked “Krebs Uric Acid Cycle”. Metabolism at a Glance offers an accessible introduction to metabolism, and is ideal as a revision aid for students preparing for undergraduate and USMLE Step 1 exams. Contents Preface Part 1 Energy metabolism 1 Introduction to metabolic pathways 2 Biosynthesis of ATP I: ATP, the molecule that powers metabolism 3 Biosynthesis of ATP II: mitochondrial respiratory chain 4 The oxidation of cytosolic NADH: the malate/aspartate shuttle and the glycerol phosphate shuttle 5 Metabolism of glucose to provide energy 6 Metabolism of one molecule of glucose yields 31 (or should it be 38?) molecules of ATP 7 Anaerobic metabolism of glucose and glycogen to yield energy as ATP 8 2,3-Bisphosphoglycerate (2,3-BPG) and the red blood cell 9 Metabolism of triacylglycerol to provide energy as ATP Part 2 Carbohydrate metabolism 10 Metabolism of glucose to glycogen 11 Glycogen metabolism I 12 Glycogen metabolism II 13 Glycogen metabolism III: regulation of glycogen breakdown (glycogenolysis) 14 Glycogen metabolism IV: regulation of glycogen synthesis (glycogenesis) 15 The pentose phosphate pathway: the production of NADPH and reduced glutathione 16 Regulation of glycolysis: overview exemplified by glycolysis in cardiac muscle 17 Glycolysis in skeletal muscle: biochemistry of sport and exercise 18 Regulation of gluconeogenesis 19 Regulation of Krebs cycle 20 Mammals cannot synthesize glucose from fatty acids 21 Supermouse: overexpression of cytosolic PEPCK in skeletal muscle causes super-athletic performance 22 Sorbitol, galactitol, glucuronate and xylitol 23 Fructose metabolism 24 Metabolism of ethanol Part 3 Fat metabolism 25 The pyruvate/malate cycle and the production of NADPH 26 Metabolism of glucose to fat (triacylglycerol) 27 Metabolism of glucose to fatty acids and triacylglycerol 28 Glycolysis and the pentose phosphate pathway collaborate in liver to make fat 29 Esterification of fatty acids to triacylglycerol (TAG) in liver and white adipose tissue 30 Mobilisation of fatty acids from adipose tissue: part 1 Regulation of lipolysis 31 Mobilisation of fatty acids from adipose tissue: part 2 the triacylglycerol/fatty acid cycle 32 Glyceroneogenesis 33 Metabolism of protein to fat after feeding 34 Elongation and desaturation of fatty acids 35 â-oxidation of fatty acids and the carnitine shuttle 36 The ketone bodies 37 Ketone body utilization 38 â-oxidation of unsaturated fatty acids 39 Peroxisomal â-oxidation of fatty acids 40 á- and â-oxidation of fatty acids 41 ù-oxidation of fatty acids Part 4 Steroid metabolism 42 Cholesterol 43 Steroid Hormones and Bile Salts Part 5 Amino acid metabolism 44 Biosynthesis of the non-essential amino acids 45 Catabolism of amino acids I 46 Catabolism of amino acids II 47 Metabolism of amino acids to glucose in starvation and during the period immediately after refeeding 48 Disorders of amino acid metabolism 49 Phenylalanine and tyrosine metabolism 50 Tryptophan metabolism: the biosynthesis of NAD+, serotonin and melatonin 51 The ornithine cycle for the production of urea: ‘the urea cycle’ Part 6 Metabolic channelling 52 Metabolic channelling I: enzymes are organized to enable channelling of metabolic intermediates 53 Metabolic Channelling II: Fatty acid synthase Part 7 Purines, pyrimidines and porphyrins 54 Amino acid metabolism, folate metabolism and the ‘1-carbon pool’ I: purine biosynthesis 55 Amino acid metabolism, folate metabolism and the ‘1-carbon pool’ II: pyrimidine biosynthesis 56 The Krebs Uric Acid Cycle for the disposal of nitrogenous waste 57 Porphyrin metabolism, haem and the bile pigments Part 8 Integration of metabolic pathways and diabetes 58 Metabolic pathways in fasting liver and their disorder in Reye’s syndrome 59 Diabetes I: metabolic changes in diabetes 60 Diabetes II: T1DM, T2DM, MODY and pancreatic â-cell metabolism 61 Diabetes III: Type 2 Diabetes mellitus (T2DM) and dysfunctional liver metabolism Index
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