In the past decade there have been enormous advances in our understanding of frontotemporal dementia and related syndromes. The impetus for these advances has come from a number of directions including genetic discoveries, new approaches to neuroimaging and improved neuropsychological understanding of the cognitive aspects of the condition. This book provides a much needed review of the current status of our knowledge of these syndromes. The book starts with chapters reviewing the history of the condition and describes the presenting clinical, neuropsychiatric and neuropsychological features, before reviewing, in detail, the areas of greatest recent research progress. The book concludes with a chapter proposing a multidisciplinary approach to patient management. Frontotemporal Dementia Syndromes will be essential reading for neurologists, psychologists, psychiatrists and other clinicians interested in cognitive and behavioural disorders, as well as to basic scientists working in the area of neurodegeneration.
• Provides a comprehensive update of a dynamic area of research from a team at the forefront of the field • Covers the very latest advances from the fields of genetics, neuroimaging and neuropsychology • Proposes a multidisciplinary approach to patient management
Preface John R. Hodges; 1. Overview of frontotemporal dementia John R. Hodges; 2. Epidemiology of frontotemporal dementia Andrew Graham; 3. Clinical presentations of frontotemporal dementia Christopher M. Kipps, Jonathan A. Knibb and John R. Hodges; 4. Overlap syndromes Thomas H. Bak; 5. The neuropsychology of frontotemporal dementia John R. Hodges, Karalyn Patterson; 6. Neuroimaging and other investigative findings Peter J. Nestor; 7. The histopathology of frontotemporal dementia R. Rhys Davies and John H. Xuereb; 8. Molecular neuropathology in familial and sporadic frontotemporal dementia Laura Gasparini and Maria Grazia Spillantani; 9. The genetics of frontotemporal dementia Jeremy Brown; 10. Psychological interventions in frontemporal dementia Sinclair Lough and Vanessa Garfoot.
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