This book, now in its fourth edition, is unique in detailing in depth the technological basis of radiation therapy. Compared with the previous edition, all chapters have been rewritten and updated. In addition, new chapters have been included on various topics, including the use of imaging in treatment planning, second malignant neoplasms due to irradiation, and quality assurance in radiation oncology. The book is divided into two sections. The first covers basic concepts in treatment planning, including essential physics, and explains the various approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, and high and low dose rate brachytherapy. The second part documents the practical clinical applications of these concepts in the treatment of different cancers. All of the chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students and practitioners in the various fields of oncology with the basic technological factors and approaches in radiation therapy.
Basic Concepts in Treatment Planning: Modeling Therapeutic Ratios for Different Fractionation Schedules.- Malignant Tumors Following Irradiation.- Clinical Principles & Applications of Chemoirradiation.- Imaging in Radiation Therapy.- Physics of Treatment Planning in Radiation Oncology.- The Simulation Process in the Determination and Definition of the Treatment Volume and Treatment Planning.- Electron Beam Therapy.- Treatment Aids for External Beam Radiotherapy.- 3-D Planning and Conformal Therapy.- Intensity Modulated Rad. Therapy.- Stereotactic Radiosurgery & Radiotherapy.- Physics of Brachytherapy.- Radiobiology and Clin. Applications of Low and High Dose Rate Brachytherapy.- Quality Assurance in Radiation Oncology. Practical Clinical Applications: CNS Tumors.- Head & Neck and Breast Cancer, Carcinoma of the Esophagus; Lung Cancer.- Cancers of the Colon, Rectum, Anus; Bladder Cancer.- Low-Dose Rate-Brachytherapy for Carcinoma of the Cervix.- Technical Aspects of Rad. Therapy for Endometrial Carcinoma.- Carcinoma of the Vulva and Vagina.-Prostate and Testicular Cancer.-Extremity Soft Tissue Sarcoma in Adults.- Total Body Irradiation in Conditioning Regimens for Bone Marrow Transplantation.- Hodgkin's Disease.- Techn. For Intravascular Brachytherapy.- Subject Index.- List of Contributors